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Nitrous oxide misuse reported to two United States data systems during 2000-2019
1Independent Researcher, Austin, Texas, USA.
Journal of Addictive Diseases
|September 3, 2020
Summary
Nitrous oxide misuse, particularly among young males, significantly increased from 2000-2019 according to US emergency department and adverse event data. Most cases involved individuals aged 13-39 years.
Area of Science:
- Public Health
- Toxicology
- Emergency Medicine
Background:
- Nitrous oxide (N2O) is increasingly misused for its psychoactive effects.
- Reports indicate a rise in recreational nitrous oxide abuse.
- Understanding misuse patterns is crucial for public health interventions.
Purpose of the Study:
- To analyze trends and characteristics of nitrous oxide misuse.
- To describe cases reported to two major US data systems.
Main Methods:
- Retrospective analysis of cases from the National Electronic Injury Surveillance System (NEISS) and the Food and Drug Administration Adverse Event Reporting System (FAERS).
- Data collected from 2000 to 2019.
- Analysis of patient demographics, outcomes, and reporting trends.
Main Results:
- Nitrous oxide misuse reports increased substantially after 2013 in both NEISS and FAERS.
- The majority of misused patients were males aged 13-39 years.
- Most NEISS cases resulted in emergency department treatment and release; FAERS cases were predominantly classified as serious.
Conclusions:
- Both NEISS and FAERS data show a significant upward trend in nitrous oxide misuse from 2000-2019.
- Young males represent the primary demographic affected by nitrous oxide misuse.
- The findings highlight the growing public health concern associated with nitrous oxide abuse.
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