Jove
Visualize
Contact Us

Related Concept Videos

Testosterone: Functions and Regulation01:26

Testosterone: Functions and Regulation

1.7K
The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...
1.7K
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

3.8K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
3.8K
Therapeutic Drug Monitoring: Affecting Factors01:29

Therapeutic Drug Monitoring: Affecting Factors

107
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
107
Adrenal Gland Disorders01:27

Adrenal Gland Disorders

2.7K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
2.7K
Signs of Puberty01:27

Signs of Puberty

1.1K
Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
1.1K
Drug Therapy01:28

Drug Therapy

185
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
185

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of testosterone therapy and hypogonadism on treatment outcomes in Peyronie's disease: a multicenter retrospective analysis of collagenase clostridium histolyticum therapy.

The journal of sexual medicine·2026
Same author

Clinical outcomes in Peyronie's disease: impact of curvature severity and disease phase on symptom resolution and treatment response.

The journal of sexual medicine·2026
Same author

Sexual Health.

The Journal of urology·2026
Same author

Efficacy and safety of collagenase <i>Clostridium histolyticum</i> in men who have sex with men.

Sexual medicine·2026
Same author

The interplay between testosterone and depression: bridging research, clinical applications, and health: a narrative review.

Sexual medicine reviews·2026
Same author

The use of radiofrequency in the treatment of erectile dysfunction.

The journal of sexual medicine·2026
Same journal

Smarter, Not More: The Rationale for Reducing Systematic Cores in the MRI-Targeted Biopsy Era.

The Canadian journal of urology·2026
Same journal

Ten Years of Progress in Advanced Prostate Cancer at the AUA.

The Canadian journal of urology·2026
Same journal

Electroacupuncture for sperm improvement in varicocele: a case report.

The Canadian journal of urology·2026
Same journal

Transperineal approach for penetrating injury of corpus spongiosum and bulbous urethra caused by vesicourethral foreign body: a case report.

The Canadian journal of urology·2026
Same journal

Penile fracture and concomitant severe urethral trauma-a case report and discussion of surgical approach.

The Canadian journal of urology·2026
Same journal

Management of retained bullet fragments from posterior urethra after gunshot wound: a case report.

The Canadian journal of urology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Dec 10, 2025

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
11:51

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

15.5K

Controversies with testosterone therapy.

Mohit Khera1

  • 1Department of Urology, Baylor College of Medicine, Houston, Texas, USA.

The Canadian Journal of Urology
|September 3, 2020
PubMed
Summary
This summary is machine-generated.

Testosterone therapy (TTh) in hypogonadal men shows no significant link to cardiovascular events, prostate cancer, or BPH. Lifestyle changes can improve testosterone levels, but more research is needed.

More Related Videos

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

1.2K
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
07:25

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

13.6K

Related Experiment Videos

Last Updated: Dec 10, 2025

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
11:51

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

15.5K
Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

1.2K
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
07:25

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

13.6K

Area of Science:

  • Endocrinology
  • Men's Health
  • Urology

Background:

  • Concerns exist regarding testosterone therapy (TTh) safety in hypogonadal men.
  • Potential links to cardiovascular (CV) events, prostate cancer, and benign prostatic hyperplasia (BPH) are debated.
  • Appropriate patient selection and the role of lifestyle modification in TTh are controversial.

Purpose of the Study:

  • To review the literature on testosterone therapy (TTh) and its association with CV events, prostate cancer, BPH, and lifestyle modifications.
  • To clarify the risks and benefits of TTh in hypogonadal men.
  • To assess the impact of lifestyle interventions on testosterone levels.

Main Methods:

  • A comprehensive literature review was conducted.
  • Articles assessing testosterone therapy (TTh) and its association with CV events, prostate cancer, BPH, and lifestyle modification were analyzed.

Main Results:

  • Low testosterone levels are linked to increased CV events, but TTh's role in increasing CV risk is inconclusive.
  • No evidence links TTh to prostate cancer development or worsening BPH symptoms.
  • Lifestyle modifications like weight loss and improved sleep can enhance testosterone levels in hypogonadal men.

Conclusions:

  • Current literature does not indicate significant risks of TTh concerning prostate cancer, BPH, or CV events.
  • Further research, including randomized controlled trials, is necessary to confirm these findings.
  • Patients should be informed about TTh indications, potential benefits of lifestyle changes, and risks before treatment initiation.