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Miguel A Vences1, Carol Manrique Villegas2, Julissa Mogollon-Lavi3

  • 1Departamento de Neurología, Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú.

Revista Peruana De Medicina Experimental Y Salud Publica
|September 3, 2020
PubMed
Summary
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Critical asthma syndrome, a severe exacerbation, can be mimicked by allergic bronchopulmonary aspergillosis. Early diagnosis and treatment with antifungals and steroids improve outcomes in difficult-to-control asthma patients.

Area of Science:

  • Pulmonology
  • Infectious Diseases

Background:

  • Critical asthma syndrome represents the most severe outcome of acute asthma exacerbations.
  • Allergic bronchopulmonary aspergillosis (ABPA) frequently mimics critical asthma syndrome, posing a significant mortality risk if not diagnosed promptly in patients with difficult-to-control asthma.

Observation:

  • A 15-year-old male presented to the ICU with critical asthma symptoms.
  • Diagnosis of ABPA was established in this patient.

Findings:

  • The patient showed a favorable response to voriconazole and corticosteroids.
  • This case highlights the importance of considering ABPA in patients with critical asthma or difficult-to-control chronic lung disease.

Implications:

  • Early diagnosis and treatment of ABPA in critical asthma can significantly improve patient prognosis and quality of life.

Related Experiment Videos

  • Clinicians should consider ABPA in the differential diagnosis for severe, refractory asthma cases.