Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intracellular Movement of Viruses and Bacteria01:10

Intracellular Movement of Viruses and Bacteria

3.3K
Intracellular bacteria and viruses often comprise a group of highly infectious pathogens that can cause several diseases. Bacterial pathogens include those belonging to the genus Rickettsia responsible for conditions such as rocky mountain spotted fever and the Mediterranean spotted fever; Chlamydia, a genus responsible for a sexually transmitted disease; Coxiella burnetii, an agent responsible for Q fever. Viral pathogens include vaccinia—a poxvirus, and herpes simplex virus—a...
3.3K
Bacterial Phylum Chlamydiae01:29

Bacterial Phylum Chlamydiae

314
The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic...
314
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

386
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
386
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

5.9K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
5.9K
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

278
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
278
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

240
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
240

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Second day of the interdisciplinary group dedicated to phage therapy and biocontrol].

Virologie (Montrouge, France)·2026
Same author

Guidelines for Lyme borreliosis: clinical manifestations.

Infectious diseases now·2025
Same author

[Commercialization in Europe of a new bacteriophage-based food additive within the 'One Health' context: what do regulatory authorities say?]

Virologie (Montrouge, France)·2025
Same author

Acceptance of chikungunya vaccination: a rapid survey in Reunion island during an epidemic.

Vaccine·2025
Same author

Updates on Donor-Derived Infection in Solid Organ Transplantation, Report from the 2024 GTI (Infection and Transplantation Group) Annual Meeting.

Transplant international : official journal of the European Society for Organ Transplantation·2025
Same author

Compliance with antimicrobial stewardship guidelines in surgery: an observational, multidisciplinary, cohort study.

World journal of emergency surgery : WJES·2025
Same journal

[Prolonged fever].

La Revue du praticien·2026
Same journal

[Lower gastrointestinal bleeding].

La Revue du praticien·2026
Same journal

[Management of antiplatelet agents and oral anticoagulants in cases of gastrointestinal bleeding].

La Revue du praticien·2026
Same journal

[A history of child abuse intervention in the West].

La Revue du praticien·2026
Same journal

[Agranulocytose médicamenteuse].

La Revue du praticien·2026
Same journal

[Patient education in heart failure].

La Revue du praticien·2026
See all related articles

Related Experiment Video

Updated: Dec 10, 2025

An Electroporation Method to Transform Rickettsia spp. with a Fluorescent Protein-Expressing Shuttle Vector in Tick Cell Lines
07:18

An Electroporation Method to Transform Rickettsia spp. with a Fluorescent Protein-Expressing Shuttle Vector in Tick Cell Lines

Published on: October 11, 2022

2.3K

[Rickettsioses].

Carole Eldin1, Philippe Parola1

  • 1Aix-Marseille Université, IRD, AP-HM, SSA, VITROME ; IHU-Méditerranée Infection ; Centre de référence pour la prise en charge des maladies vectorielles à tiques, Marseille, France.

La Revue Du Praticien
|September 3, 2020
PubMed
Summary
This summary is machine-generated.

Rickettsioses are bacterial infections transmitted by arthropods like ticks and lice. Early doxycycline treatment is crucial for potentially fatal rickettsial diseases, even before diagnosis.

Keywords:
Rickettsia Infections

More Related Videos

Extraction of Saliva, Haemolymph, Salivary Glands, and Midgut from Individual Ticks (Acari: Ixodidae)
03:22

Extraction of Saliva, Haemolymph, Salivary Glands, and Midgut from Individual Ticks (Acari: Ixodidae)

Published on: October 31, 2025

394
Author Spotlight: Controlled Human Exposure Model for Tick Research and Lyme Disease Studies
04:47

Author Spotlight: Controlled Human Exposure Model for Tick Research and Lyme Disease Studies

Published on: December 1, 2023

956

Related Experiment Videos

Last Updated: Dec 10, 2025

An Electroporation Method to Transform Rickettsia spp. with a Fluorescent Protein-Expressing Shuttle Vector in Tick Cell Lines
07:18

An Electroporation Method to Transform Rickettsia spp. with a Fluorescent Protein-Expressing Shuttle Vector in Tick Cell Lines

Published on: October 11, 2022

2.3K
Extraction of Saliva, Haemolymph, Salivary Glands, and Midgut from Individual Ticks (Acari: Ixodidae)
03:22

Extraction of Saliva, Haemolymph, Salivary Glands, and Midgut from Individual Ticks (Acari: Ixodidae)

Published on: October 31, 2025

394
Author Spotlight: Controlled Human Exposure Model for Tick Research and Lyme Disease Studies
04:47

Author Spotlight: Controlled Human Exposure Model for Tick Research and Lyme Disease Studies

Published on: December 1, 2023

956

Area of Science:

  • Infectious Diseases
  • Bacteriology
  • Tropical Medicine

Background:

  • Rickettsioses are intracellular bacterial infections caused by bacteria of the order Rickettsiales.
  • Transmission occurs via arthropod vectors such as ticks, lice, and fleas, primarily in tropical regions.
  • These infections can present as endemic in certain areas like France or be acquired through travel, often manifesting as fever of unknown origin.

Purpose of the Study:

  • To outline the characteristics, diagnosis, and treatment of rickettsioses.
  • To highlight the challenges in laboratory diagnosis and the utility of specific diagnostic tools.
  • To emphasize the urgency of initiating treatment for rickettsioses.

Main Methods:

  • Review of rickettsial disease characteristics and transmission vectors.
  • Discussion of diagnostic approaches, including limitations of conventional blood cultures.
  • Highlighting the role of serology and PCR for diagnosis, particularly from eschar swabs.
  • Emphasis on clinical suspicion guiding early treatment decisions.

Main Results:

  • Rickettsiae are difficult to culture using standard laboratory methods.
  • Serology is a common diagnostic method, but PCR on eschar swabs offers a rapid alternative.
  • Early initiation of doxycycline is critical for managing potentially fatal rickettsial infections.

Conclusions:

  • Rickettsioses require prompt clinical suspicion and treatment with doxycycline.
  • Diagnostic confirmation may be delayed, underscoring the importance of empirical therapy.
  • Effective management hinges on recognizing clinical signs and initiating treatment before definitive diagnosis.