Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Dec 10, 2025

A Photonic System for Generating Unconditional Polarization-Entangled Photons Based on Multiple Quantum Interference
07:56

A Photonic System for Generating Unconditional Polarization-Entangled Photons Based on Multiple Quantum Interference

Published on: September 5, 2019

8.8K

Improving Paralysis Compensation in Photon Counting Detectors.

Scott S Hsieh, Kris Iniewski

    IEEE Transactions on Medical Imaging
    |September 3, 2020
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A pilot study: dual-contrast arthrography using photon-counting detector computed tomography with gadolinium and iodine contrasts.

    Physics in medicine and biology·2026
    Same author

    Hallucination at low radiation dose: Evaluation of two deep-learning reconstruction methods in high-resolution chest CT.

    Proceedings of SPIE--the International Society for Optical Engineering·2026
    Same author

    Design of a next-generation conventional scintillator x-ray detector: Improved spatial resolution and fill factor.

    Medical physics·2026
    Same author

    A framework for quantifying and leveraging uncertainty in pre-trained CT denoising model.

    IEEE transactions on bio-medical engineering·2026
    Same author

    Color CT, literally.

    Proceedings of SPIE--the International Society for Optical Engineering·2026
    Same author

    System design options for a high-resolution, conventional scintillator detector.

    Proceedings of SPIE--the International Society for Optical Engineering·2026

    This study introduces a novel paralysis compensation mechanism for photon counting detectors (PCDs). The enhanced retrigger architecture with secondary counters effectively reduces noise across moderate and high flux conditions.

    Area of Science:

    • Medical Imaging
    • Detector Physics

    Background:

    • Photon counting detectors (PCDs) exhibit paralyzable or nonparalyzable behavior.
    • Detector paralysis limits sensitivity to incoming radiation flux.
    • Application-specific integrated circuits (ASICs) are used to embed paralysis compensation electronics.

    Purpose of the Study:

    • To evaluate the incremental benefit of three paralysis compensation mechanisms for PCDs.
    • To propose a novel retrigger architecture with dedicated secondary counters.
    • To analyze the impact of these mechanisms on basis material decomposition noise.

    Main Methods:

    • Monte Carlo simulations were used to model spectral response.
    • Cramér-Rao lower bound (CRLB) was employed to estimate variance in basis material decomposition.

    More Related Videos

    An Optimized Single-Molecule Pull-Down Assay for Quantification of Protein Phosphorylation
    07:45

    An Optimized Single-Molecule Pull-Down Assay for Quantification of Protein Phosphorylation

    Published on: June 6, 2022

    3.2K
    Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source
    12:19

    Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source

    Published on: April 4, 2017

    8.7K

    Related Experiment Videos

    Last Updated: Dec 10, 2025

    A Photonic System for Generating Unconditional Polarization-Entangled Photons Based on Multiple Quantum Interference
    07:56

    A Photonic System for Generating Unconditional Polarization-Entangled Photons Based on Multiple Quantum Interference

    Published on: September 5, 2019

    8.8K
    An Optimized Single-Molecule Pull-Down Assay for Quantification of Protein Phosphorylation
    07:45

    An Optimized Single-Molecule Pull-Down Assay for Quantification of Protein Phosphorylation

    Published on: June 6, 2022

    3.2K
    Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source
    12:19

    Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source

    Published on: April 4, 2017

    8.7K
  • Simulations compared a standard PCD, pileup trigger, retrigger architecture, and the proposed enhanced retrigger architecture.
  • Main Results:

    • Without compensation, noise increases sharply at moderate and high flux due to contrast inversion.
    • The pileup trigger reduces high-flux noise but doesn't eliminate contrast inversion.
    • The retrigger architecture eliminates contrast inversion but not high-flux noise.
    • The proposed retrigger architecture with secondary counters reduces noise at both moderate and high flux.

    Conclusions:

    • The proposed retrigger architecture with dedicated secondary counters offers superior noise reduction compared to existing methods.
    • This enhancement improves the performance of PCDs, particularly under varying flux conditions.
    • The findings are crucial for optimizing image quality in applications relying on PCDs.