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RSV M2-1 Protein in Complex with RNA: Old Questions Are Answered and a New One Emerges
Victoria Anne Kleiner1, Rachel Fearns1
1Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA.
Structure (London, England : 1993)
|September 3, 2020
Abstract:
The respiratory syncytial virus (RSV) M2-1 protein is essential for virus transcription. In this issue of Structure, Gao et al. (2020) describe the crystal structure of M2-1 in complex with RNA. This structure provides new insight into the RSV transcription mechanism but also raises an intriguing question regarding M2-1's function.