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PPARγ enhanced Adiponectin polymerization and trafficking by promoting RUVBL2 expression during adipogenic

Daiyun Zhu1, Le Xu2, Xuan Wei2

  • 1College of Animal Science and Technology & College of Veterinary Medicine, Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan 430070, PR China.

Gene
|September 3, 2020
PubMed
Summary

Peroxisome proliferator-activated receptor gamma (PPARγ) promotes adipocyte differentiation by activating RUVBL2 transcription. This process enhances adiponectin secretion, crucial for adipose tissue development and metabolic health.

Keywords:
Adipocyte differentiationAdiponectinPPARγPromoterRUVBL2

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