Analytical performance of functional nanostructured biointerfaces for sensing phenolic compounds

Electrochemical biointerfaces are constructed with a wide range of nanomaterials and conducting polymers that strongly affect the analytical performance of biosensors. The analysis of progress toward electrochemical sensing platforms offers opportunities to provide devices for commercial use. The investigation of different methods for the synthesis of phenol biointerfaces leads to design challenges in the field of monitoring phenolic compounds. This paper review the innovative strategies and feature techniques in the construction of phenolic compound biosensors. The focus was made on the preparation methods of nanostructures and nanomaterials design for catalytic improvements of sensing interfaces. The paper also provides a comprehensive overview in the field of enzyme immobilization approaches at solid supports and technical formation of polymer nanocomposites, as well as applications of hybrid organic-inorganic nanocomposites in phenolic biosensors. This review also highlights the recent progress in the electrochemical detection of phenolic compounds and summarizes analytical performance parameters including sensitivity, storage stability, limit of detection, linear range, and Michaelis-Menten kinetic analysis. It also emphasizes advances from the past decade including technical challenges for the construction of suitable biointerfaces for monitoring phenolic compounds.