Related Experiment Video
Updated: Dec 10, 2025
08:12
Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
10.5K
Stannous Fluoride Effects on Enamel: A Systematic Review.
Luca Fiorillo1,2, Gabriele Cervino1, Alan Scott Herford3
1Department of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, Italy.
Biomimetics (Basel, Switzerland)
|September 4, 2020
Summary
Stannous fluoride (SnF2) in toothpaste shows no significant health risks and offers benefits for enamel health and stain removal. Clinical trials indicate its effectiveness in reducing enamel loss, supporting its use in oral hygiene products.
Area of Science:
- Oral Health
- Dental Materials Science
- Fluoride Chemistry
Background:
- Stannous fluoride (SnF2) is a compound used in some toothpastes, but its safety and efficacy are debated.
- Concerns exist regarding potential negative health effects of stannous fluoride.
- Dosage of stannous fluoride in toothpastes is typically measured in parts per million (ppm).
Purpose of the Study:
- To systematically review randomized clinical trials on stannous fluoride over the past decade.
- To clarify the function and safety of stannous fluoride in dental applications.
- To provide evidence-based conclusions on the use of stannous fluoride in toothpaste.
Main Methods:
- Systematic literature review of randomized clinical trials published within the last 10 years.
- Initial search yielded over 800 results, narrowed down to 26 relevant manuscripts after applying inclusion/exclusion criteria.
- Manual analysis of selected studies was performed, including a Mann-Whitney U Test for statistical comparison.
Main Results:
- Stannous fluoride (SnF2) does not present significant contraindications beyond those generally associated with fluoride.
- A meta-analysis on enamel loss demonstrated that products containing stannous fluoride yielded superior results (p < 0.05).
Conclusions:
- Stannous fluoride shows promise in promoting enamel erosion resistance and recalcification.
- The compound may positively impact biofilm formation and reduce gingival inflammation.
- Stannous fluoride could be beneficial for tooth stain removal and combating halitosis.
Related Concept Videos
01:31Essential Minerals for Bone Health
5.6K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
5.6K
01:21Tooth Anatomy
1.8K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
1.8K
01:26Minerals
859
Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
Major...
Major...
859
01:18Effects of EDTA on End-Point Detection Methods
530
Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a...
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a...
530