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Updated: Dec 10, 2025

The Use of Gas Chromatography to Analyze Compositional Changes of Fatty Acids in Rat Liver Tissue during Pregnancy
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COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman

Abigail Anness1, Farah Siddiqui2

  • 1Department of Obstetrics and Gynaecology, University Hospitals of Leicester NHS Trust, Leicester, UK abigailanness@gmail.com.

BMJ Case Reports
|September 4, 2020
PubMed

The COVID-19 outbreak has spread across the globe at an alarming rate. As the pandemic escalates, experience of COVID-19 in pregnant women is accumulating. We present a case of COVID-19 pneumonia in a 28-week pregnant woman with a known low lying placenta. The patient had deranged liver function tests at presentation, along with elevated bile acids. We discuss the differential diagnosis of these findings, and the possible mechanisms of hepatic injury in COVID-19. The low lying placenta in this patient meant that we had to carefully consider the application of recommendations for thromboprophylaxis in pregnant COVID-19 patients. With supportive management, this patient improved enough to be discharged, and has gone on to deliver a healthy neonate at term.

Keywords:
infectious diseasesliver diseaseobstetrics and gynaecologypregnancy

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