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Precision pathology as applied to breast core needle biopsy evaluation: implications for management
1Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 02215, USA. lcollins@bidmc.harvard.edu.
Summary
Pathologists play a crucial role in diagnosing breast disease via core needle biopsy. Accurate diagnoses are essential as surgical excision is often bypassed, making the biopsy the sole diagnostic opportunity.
Area of Science:
- Oncology
- Pathology
- Breast Imaging
Background:
- Shifting paradigms in breast cancer management involve de-escalation of therapy and reduced surgical excision for high-risk lesions.
- Increased utilization of neoadjuvant systemic therapy alters the diagnostic pathway for breast conditions.
Purpose of the Study:
- To emphasize the critical role of pathologists in guiding breast disease management.
- To highlight the significance of accurate core needle biopsy diagnoses in the current clinical landscape.
Main Methods:
- Review of current trends in breast cancer treatment and diagnosis.
- Analysis of the impact of neoadjuvant therapy on diagnostic procedures.
Main Results:
- Core needle biopsy is increasingly the definitive diagnostic tool for breast lesions.
- The opportunity for confirmatory diagnosis via surgical excision is diminishing.
Conclusions:
- Pathologists must ensure high accuracy and precision in core needle biopsy diagnoses.
- Core needle biopsy is often the only diagnostic procedure, underscoring its critical importance in patient management.
