Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Antibiotics in surgery. An overview.

¹Department of Surgery, University of New Mexico School of Medicine, Albuquerque 87131.

American Journal of Surgery

|May 31, 1988

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The alimentary absorption of diamorphine and morphine in man as indicated by urinary excretion studies.

British journal of clinical pharmacology·2012

Same author

Profile. Donald E. Fry. Interview by Vicki Glaser.

Surgical infections·2005

Same author

Basic aspects of and general problems in surgical infections.

Surgical infections·2003

Same author

Herpesviruses: emerging nosocomial pathogens?

Surgical infections·2003

Same author

Multiple organ dysfunction syndrome: past, present and future.

Surgical infections·2003

Same author

The consequences of suppression of anaerobic bacteria.

Surgical infections·2003

Same journal

Innovative management of Anterior Cutaneous Nerve Entrapment Syndrome (ACNES): A meta-analysis and introduction of a new robotic approach with patient-based algorithm.

American journal of surgery·2026

Same journal

Does the risk outweigh the benefit? Clot progression, recanalization & complications of anticoagulation therapy in acute pancreatitis with concomitant splanchnic vein thrombosis.

American journal of surgery·2026

Same journal

High and low body mass index and 90-day postoperative outcomes in patients with Crohn's disease undergoing abdominal surgery.

American journal of surgery·2026

Same journal

Women with firearm injuries: A multicenter mixed-methods study.

American journal of surgery·2026

Same journal

SBAS presidential address: A surgeon-scientist's journey from haptic science to digital performance metrics.

American journal of surgery·2026

Same journal

Using Dr. Google and AI to stay informed.

American journal of surgery·2026

See all related articles

Antibiotic use in surgery involves prevention and treating infections. Current broad-spectrum antibiotics show comparable results, suggesting future research should focus on optimizing drug properties rather than spectrum alone.

Area of Science:

Infectious Diseases
Surgical Care
Pharmacology

Background:

Antibiotic use in surgical patients presents unique challenges, including prophylactic administration in high-risk procedures and treatment of polymicrobial infections.
This has driven the development and investigation of broad-spectrum antimicrobial agents.

Purpose of the Study:

To evaluate the current landscape of antibiotic utilization in surgical patients.
To identify the optimal antibiotic strategies for both preventive and therapeutic indications in surgery.

Main Methods:

Review of existing literature on antibiotic use in surgical settings.
Comparative analysis of different antibiotic agents and combinations for efficacy and safety.

Main Results:

Related Experiment Videos

Numerous antibiotics and combinations demonstrate comparable clinical outcomes for both preventive and therapeutic uses in surgery.
No single antibiotic or combination has emerged as superior for these indications.

Conclusions:

The pursuit of broader-spectrum antibiotics may not yield improved clinical outcomes in surgical patients.
Future research should prioritize optimizing pharmacologic, toxicologic, and economic profiles of antibiotics while maintaining comparable clinical efficacy.