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Related Experiment Video

Updated: Dec 10, 2025

Novel Process for 3D Printing Decellularized Matrices
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Human Acellular Dermal Matrix Augmentation Phalloplasty Surgery.

Huimin Zhang1, Chengyue Jin2, Peiyang Zhang3

  • 1Department of Urology, Tangshan Gongren Hospital, Tangshan, Hebei, China.

Plastic Surgery (Oakville, Ont.)
|September 4, 2020
PubMed
Summary

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Human acellular dermal matrix allograft effectively and safely enhances penile girth for psychological and functional benefits. This augmentation phalloplasty technique shows lasting results and high patient acceptance.

Area of Science:

  • Urology
  • Plastic Surgery
  • Regenerative Medicine

Background:

  • Penile augmentation is sought for psychological and partner satisfaction.
  • Existing surgical techniques lack a definitive gold standard.

Purpose of the Study:

  • To evaluate the efficacy and safety of human acellular dermal matrix allograft in augmentation phalloplasty.

Main Methods:

  • 182 patients underwent augmentation phalloplasty using human acellular dermal matrix allograft.
  • Graft placement involved suturing to Buck's fascia, with careful attention to the urethra.
  • Measurements of penile circumference were taken pre- and post-operatively.

Main Results:

  • Significant increases in both flaccid (7.03 cm to 8.07 cm) and erect (12.1 cm to 12.79 cm) penile girth were observed after one year (P < .05).
Keywords:
allograftdermalpenile augmentation

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  • The majority of patients reported improved sexual self-esteem and function.
  • 59 patients experienced alleviation of premature ejaculation.

    • Conclusions:

    • Human acellular dermal matrix allograft offers advantages over autologous dermis-fat and xenografts.
    • This method avoids donor site morbidity and provides durable results of at least one year.
    • The allograft demonstrates high patient acceptance.