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Gummatous Syphilis: A Rare Entity Mimicking Carcinoma Penis
Jeni Mathew1, Aditya Prakash Sharma1, Rajiv Ranjan1
1Department of Urology, PGIMER, Chandigarh, India.
Objective:
To describe a rare case of gummatous syphilis of the penis with urethrocutaneous fistula mimicking penile carcinoma causing a diagnostic dilemma.
Method:
A 54 year old man presented with an ulcerative lesion on glans penis. Patient was managed with partial penectomy in view of erosive growth giving rise to urethrocutaneous fistula.
Results:
Histopathology showed granulation tissue, necrotizing vasculitis and epithelioid cell granuloma. Immunohistochemistry stained positive for Treponema and patient was treated accordingly.
Conclusion:
Syphilis is rarely encountered in daily clinical practice in the penicillin era. Despite a negative serology and the clinical picture highly suggestive of malignancy, the histopathology helped in clinching the rare diagnosis.
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