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Published on: April 1, 2022
Distal revascularization and interval ligation for dialysis access-related ischemia is best performed using arm vein
M Libby Weaver1, Courtenay M Holscher1, Alexis Graham1
1Department of Surgery, The Johns Hopkins Hospital, Baltimore, Md.
Insights
Distal revascularization and interval ligation (DRIL) using an arm vein conduit offers similar symptom relief and access patency to the great saphenous vein (GSV) conduit. Arm vein DRIL significantly reduces wound complications and avoids general anesthesia.
Area of Science:
- Vascular Surgery
- Dialysis Access Management
Background:
- Distal revascularization and interval ligation (DRIL) effectively manages hemodialysis access-related ischemia.
- The great saphenous vein (GSV) is the traditional conduit, but ipsilateral arm veins may offer benefits like reduced morbidity and suitability for regional anesthesia.
Purpose of the Study:
- To compare the suitability and outcomes of DRIL procedures using an arm vein conduit versus a GSV conduit.
Main Methods:
- Retrospective review of 66 patients undergoing DRIL from 2008-2019.
- Comparison of patient characteristics, access patency (Kaplan-Meier), and complication rates between arm vein and GSV conduit groups.
- Statistical analysis using Wilcoxon log-rank and chi-squared tests.
Main Results:
- No significant difference in access patency between arm vein (86.9% at 12 months) and GSV (93.8% at 12 months) conduits.
- Symptom resolution was achieved in nearly all patients across both groups.
- Significantly lower incidence of wound complications in the arm vein group (11%) compared to the GSV group (46%).
Conclusions:
- DRIL using an ipsilateral arm vein conduit is a viable alternative to the GSV conduit.
- Arm vein conduits demonstrate comparable efficacy in symptom resolution and access salvage with fewer wound complications.
- The use of an arm vein conduit for DRIL is recommended when available, potentially avoiding general anesthesia.
Objective:
Distal revascularization and interval ligation (DRIL) is an effective approach to the management of hemodialysis access-related ischemia that offers both symptom relief and access salvage. The great saphenous vein (GSV) has been the most commonly used conduit. However, the use of an ipsilateral arm vein will allow for performance of the operation with the patient under regional anesthesia and might result in lower harvest site morbidity than the GSV. We sought to determine the suitability of DRIL using an arm vein compared with a GSV conduit.
Methods:
All patients who had undergone DRIL from 2008 to 2019 were retrospectively identified in the electronic medical records. The characteristics and outcomes of those with an arm vein vs a GSV conduit were compared using the Wilcoxon log-rank and χ2 tests. Access patency was examined using Kaplan-Meier methods, with censoring at lost to follow-up or death.
Results:
A total of 66 patients who had undergone DRIL for hand ischemia were included in the present study. An arm vein conduit was used in 40 patients (median age, 65 years; 25% male) and a GSV conduit in 26 patients (median age, 58 years; 19% male). No significant differences in comorbidities were found between the two groups, with the exception of diabetes mellitus (arm vein group, 78%; GSV group, 50% GSV; P = .02). No difference in the ischemia stage at presentation was present between the groups, with most patients presenting with stage 3 ischemia. Also, no differences in patency of hemodialysis access after DRIL between the two groups were found (P = .96). At 12 and 24 months after DRIL, 86.9% (95% confidence interval [CI], 68.3%-94.9%) and 82.0% (95% CI, 61.3%-92.3%) of patients with an arm vein conduit had access patency compared with 93.8% (95% CI, 63.2%-99.1%) and 76.9% (95% CI, 43.0%-92.2%) of those with a GSV conduit, respectively. All but one patient had symptom resolution. The incidence of wound complications was significantly greater in the GSV group than in the arm vein group (46% vs 11%; P = .003). DRIL bypass had remained patent in all but one patient in each group, with a median follow-up of 18 months (range, 1-112 months) in the arm vein conduit group and 15 months (range, 0.25-105 months) in the GSV conduit group.
Conclusions:
DRIL procedures using an arm vein have advantages over those performed with the GSV. In our series, symptom resolution and access salvage were similar but distinctly fewer wound complications had occurred in the arm vein group. Additionally, the use of an arm vein conduit avoids the need for general anesthesia. If an ipsilateral arm vein is available, it should be the conduit of choice when performing DRIL.
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