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Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent

Xiaoyang Bi1, Yu Chen2, Zhongya Sun3

  • 1Department of Medicinal Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China.

Bioorganic & Medicinal Chemistry Letters
|September 4, 2020
PubMed

Keywords:
Acute myeloid leukemiaBromodomainCBPDrug designInhibitor

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