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Updated: Dec 10, 2025

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
Special Issue: "Genomics and Models of Nerve Sheath Tumors"
Angela C Hirbe1, Rebecca D Dodd2, Christine A Pratilas3
1Siteman Cancer Center, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8076, St. Louis, MO 63110, USA.
Abstract:
Nerve sheath tumors arising in the context of neurofibromatosis type 1 (NF1) include benign tumors such as cutaneous, diffuse and plexiform neurofibromas; atypical neurofibromas or atypical neurofibromatosis neoplasms of uncertain biological potential (ANNUBP); and the aggressive soft tissue sarcoma, the malignant peripheral nerve sheath tumor (MPNST) [...].
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