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Updated: Dec 10, 2025

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening

Published on: October 26, 2017

Lung Cancer Screening.

Humberto K Choi¹, Peter J Mazzone¹

¹Respiratory Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Surgical Oncology Clinics of North America

|September 5, 2020

Summary

This summary is machine-generated.

Lung cancer screening using low-dose CT scans can save lives but carries risks. Integrating smoking cessation and managing findings are crucial for maximizing benefits and minimizing harms in eligible populations.

Keywords:

Low radiation dose chest CT scans Lung cancer Screening Smoking cessation interventions

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Lung Tumor Cell Recruitment Assay

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MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening

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Published on: October 26, 2017

Lung Tumor Cell Recruitment Assay

Lung Tumor Cell Recruitment Assay

Published on: February 26, 2019

Area of Science:

Pulmonology
Oncology
Radiology

Background:

Lung cancer remains the leading cause of cancer-related mortality in the United States.
Low-dose chest computed tomography (LDCT) screening is the standard of care for high-risk individuals.
Balancing the benefits and harms of lung cancer screening is essential for clinical practice.

Purpose of the Study:

To evaluate the benefits and harms associated with lung cancer screening.
To emphasize the importance of integrating smoking cessation interventions.
To highlight the need for strategies to manage screening-detected findings.

Main Methods:

This study reviews current practices and evidence regarding lung cancer screening.
It discusses the trade-offs of benefits versus harms, including overdiagnosis and complications.
The role of smoking cessation and management of incidental findings are considered.

Main Results:

Lung cancer screening offers significant benefits for high-risk populations.
Screening can lead to the identification of numerous benign lung nodules and potential overdiagnosis.
Complications associated with the screening procedure itself must be considered.

Conclusions:

Effective lung cancer screening programs require careful management of detected findings to minimize harm.
Integrating smoking cessation interventions enhances the overall clinical benefit of screening.
Future research should prioritize improved patient selection, harm reduction, and increased screening accessibility.