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Related Experiment Videos

Collaborative versus traditional method validation approach: Discussion and business case.

Ray Wickenheiser1, Laurel Farrell2

  • 1New York State Police Crime Laboratory System, Albany, NY, USA.

Forensic Science International. Synergy
|September 5, 2020
PubMed
Summary

Collaborative method validation in forensic science saves time and resources. Sharing published validation data allows other labs to perform abbreviated verification, increasing efficiency and data comparability.

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Area of Science:

  • Forensic Science
  • Laboratory Operations
  • Method Validation

Background:

  • Method validation is a time-consuming and resource-intensive process for individual Forensic Science Service Providers (FSSPs).
  • Independent validation efforts lead to duplicated work and hinder standardization across the field.

Purpose of the Study:

  • To propose and evaluate a collaborative method validation model for FSSPs.
  • To enhance efficiency, promote standardization, and reduce costs in method validation and implementation.

Main Methods:

  • Encouraging cooperative validation among FSSPs using similar technologies and methodologies.
  • Promoting the publication of validation data for new technologies, platforms, kits, or reagents in peer-reviewed journals.
  • Facilitating abbreviated method validation (verification) by FSSPs who strictly adhere to published parameters.
Keywords:
Business caseCollaborative validationMethod validationValidationVerification

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Main Results:

  • Published validation data enables other FSSPs to conduct efficient verifications, reducing development work.
  • Shared validation experiences increase operational efficiency and provide cross-checks for method validity.
  • Standardized methods and parameters allow for direct data comparison and continuous improvement.

Conclusions:

  • A collaborative method validation model significantly improves efficiency and reduces costs for FSSPs.
  • Publication of validation data is crucial for disseminating technological advancements and enabling streamlined adoption.
  • This model fosters standardization and enhances the reliability of forensic science methods through shared expertise.