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Thymic lipofibroadenoma accompanied with largish calcifications
Shuhei Hakiri1, Koji Kawaguchi2, Hisashi Tateyama3
1Department of Thoracic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. h-shuhei-1024@med.nagoya-u.ac.jp.
General Thoracic and Cardiovascular Surgery
|September 5, 2020
Summary
Thymic lipofibroadenomas are rare tumors. This case highlights how calcifications can mimic teratomas on imaging, complicating diagnosis.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Thymic lipofibroadenomas are exceptionally rare mediastinal tumors.
- Radiological features of thymic lipofibroadenomas have not been previously documented.
Observation:
- A 28-year-old male presented with an anterior mediastinal tumor containing calcifications on computed tomography (CT).
- The imaging findings were initially suspected to be a mature teratoma.
Findings:
- The resected tumor, diagnosed as lipofibroadenoma, exhibited epithelial cells within abundant fibrous stroma containing fat cells.
- Preoperative CT revealed largish calcifications, posing a diagnostic challenge in differentiating it from a teratoma.
Implications:
- This case represents the first reported radiological description of a thymic lipofibroadenoma.
- The presence of significant calcifications on CT can obscure the distinction between lipofibroadenomas and teratomas.
- Accurate preoperative diagnosis is crucial for appropriate surgical planning and patient management.
