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Overview of Exosomes

Overview of Exosomes

Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...

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Related Experiment Video

Updated: Dec 10, 2025

Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes

Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes

Published on: May 24, 2019

Exosome Profiling Pinpoints Cancer Type

Cancer Discovery

|September 5, 2020

Summary

Analyzing proteins in extracellular vesicles can differentiate tumors from healthy tissue and identify cancer types from blood plasma. These findings support the use of vesicle proteins for developing non-invasive liquid biopsies.

Area of Science:

Biochemistry
Oncology
Biotechnology

Background:

Extracellular vesicles (EVs), including exosomes, are released by cells and carry biomolecules.
Altered EV protein profiles are associated with various cancers.
Liquid biopsies offer a minimally invasive approach for cancer detection.

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Last Updated: Dec 10, 2025

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