Impact of changes to national UK Guidance on testing for gestational diabetes screening during a pandemic: a

Y van-de-l'Isle1, P J Steer2, I Watt Coote1

  • 1Department of Obstetrics, Maternal Medicine Service, St George's Hospital, London, UK.

Insights

The Royal College of Obstetricians and Gynaecologists (RCOG) Covid-19 screening for gestational diabetes (GDM) significantly reduced detection rates. This RCOG protocol missed over half of GDM cases, failing to meet National Institute for Health and Clinical Excellence (NICE) standards.

Area of Science:

  • Obstetrics and Gynecology
  • Endocrinology
  • Public Health

Background:

  • Gestational diabetes (GDM) poses risks to both mother and fetus.
  • Standardized screening protocols are crucial for timely diagnosis and management.
  • The COVID-19 pandemic necessitated adaptations in healthcare, including GDM screening.

Purpose of the Study:

  • To compare the detection rates of GDM using the National Institute for Health and Clinical Excellence (NICE) guidelines versus the Royal College of Obstetricians and Gynaecologists (RCOG) COVID-19 pandemic recommendations.
  • To evaluate the effectiveness of the RCOG's adapted GDM screening protocol during the pandemic.

Main Methods:

  • A retrospective cohort study analyzed prospectively collected data from women delivering between January 2016 and May 2020.
  • Data from a London Teaching Hospital was used.
  • Detection rates were compared between NICE and RCOG criteria, with follow-up testing for women screening negative under RCOG guidelines.

Main Results:

  • The RCOG guidance resulted in a significant decrease in GDM detection rates, from 7.7% to 4.2% (P=0.0003).
  • Of 230 women who initially tested negative under RCOG criteria but underwent further testing, 47 (20.4%) were diagnosed with GDM per NICE criteria.
  • The RCOG COVID-19 screening regime failed to detect 57% of women who were subsequently identified as having GDM.

Conclusions:

  • The RCOG COVID-19 gestational diabetes screening protocol demonstrated a significantly lower detection rate compared to NICE guidelines.
  • The adapted RCOG screening approach during the pandemic was insufficient and cannot be recommended for general use due to its failure to identify a substantial proportion of GDM cases.
  • This highlights the importance of maintaining robust GDM screening protocols even during public health crises.
Abstract

Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.1K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
2.8K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
1.8K