Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Levy-Hollister syndrome.

J M Kreutz1, H E Hoyme

  • 1Department of Pediatrics, University of Vermont, College of Medicine, Burlington.

Pediatrics
|July 1, 1988
PubMed
Summary

Levy-Hollister syndrome, a rare genetic disorder, presents with distinct facial and limb abnormalities. Early diagnosis aids in managing associated renal and hearing issues, improving patient outcomes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nutrient deficiencies in children with celiac disease during long term follow-up.

Clinical nutrition (Edinburgh, Scotland)·2023
Same author

Prenatal alcohol exposure alters the patterns of facial asymmetry.

Alcohol (Fayetteville, N.Y.)·2010
Same author

Automated diagnosis of fetal alcohol syndrome using 3D facial image analysis.

Orthodontics & craniofacial research·2008
Same author

Congenital anomaly rate in offspring of mothers with diabetes treated with insulin lispro during pregnancy.

Diabetic medicine : a journal of the British Diabetic Association·2005
Same author

The clinical picture of the Börjeson-Forssman-Lehmann syndrome in males and heterozygous females with PHF6 mutations.

Clinical genetics·2004
Same author

Pharmacogenomics: the future of drug therapy.

Clinical genetics·2002

Area of Science:

  • Genetics and Developmental Biology
  • Ophthalmology
  • Otorhinolaryngology

Background:

  • Levy-Hollister syndrome is an autosomal dominant disorder.
  • Characterized by lacrimal malformations, ear anomalies, hearing loss, hypodontia, enamel dysplasia, and upper limb malformations.
  • Renal anomalies are variably noted.

Observation:

  • A third family with Levy-Hollister syndrome was evaluated.
  • This family exhibited unusual features including bilateral nasolacrimal duct fistulas, radial aplasia, and atypical dermal ridge patterns.

Findings:

  • The study details the clinical presentation of Levy-Hollister syndrome in a new family.
  • Identified novel manifestations such as nasolacrimal duct fistulas and radial aplasia.

Implications:

  • Early recognition of Levy-Hollister syndrome is crucial.
  • Prompt investigation for renal anomalies and hearing loss is recommended.
  • Surgical intervention for lacrimal abnormalities and conductive hearing loss may reduce long-term morbidity.

Related Experiment Videos