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Poststroke depression and psychosis.

R M Dupont1, C M Cullum, D V Jeste

  • 1Department of Psychiatry, University of California, San Diego School of Medicine, La Jolla.

The Psychiatric Clinics of North America
|March 1, 1988
PubMed
Summary
This summary is machine-generated.

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Stroke can cause various neurobehavioral and psychiatric symptoms in older adults, appearing immediately or years later. While psychosis treatment lacks studies, antidepressants show promise for post-stroke depression, justifying further research.

Area of Science:

  • Neurology
  • Psychiatry
  • Geriatrics

Background:

  • Stroke frequently leads to diverse neurobehavioral syndromes in elderly individuals.
  • These syndromes encompass affective and psychotic symptoms, with variable onset post-stroke.
  • Pre-existing brain conditions can complicate the recovery from neuropsychiatric symptoms.

Purpose of the Study:

  • To review the spectrum of neurobehavioral syndromes following stroke in the elderly.
  • To discuss the implications for mental health professionals.
  • To evaluate the potential for pharmacologic interventions.

Main Methods:

  • Literature review of neurobehavioral and psychiatric sequelae of stroke.
  • Analysis of symptom presentation, timing, and influencing factors.

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  • Discussion of treatment implications based on existing evidence.

    • Main Results:

    • Stroke-induced neurobehavioral syndromes are common and varied in the elderly population.
    • Symptoms can manifest acutely or with significant delay.
    • Underlying brain disease may worsen prognosis for neuropsychiatric recovery.

    Conclusions:

    • Mental health professionals must be aware of stroke's potential psychiatric manifestations in older adults.
    • While specific treatments for post-stroke psychosis are unstudied, evidence supports antidepressant use for depression.
    • Pharmacologic treatment of neuropsychiatric symptoms post-stroke is warranted despite limited data.