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The splanchnic organs as the source of toxic mediators in shock
1Department of Surgery, Lund University, Malmö General Hospital, Sweden.
Progress in Clinical and Biological Research
|January 1, 1988
Abstract:
The splanchnic organs, and especially the pancreas and the small intestine, are susceptible to injury during ischemia and shock and the following reperfusion. This particular tissue injury is associated with a release of cardiotoxic and other toxic mediators which further aggravate the shock condition, leading to further tissue injury etc. Thereby a vicious circle is created, which is likely to contribute to collapse and death.