Related Experiment Video
Updated: Dec 9, 2025

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Evaluating a Novel Telescoping Catheter Set for Treatment of Central Venous Occlusions
Travis J Vowels1, Tony Lu2, M Mujeeb Zubair1
1Division of Vascular and Endovascular Surgery, Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, TX.
Insights
The TriForce catheter significantly improved central venous occlusion recanalization rates in end-stage renal disease patients. This novel device offers a better solution for complex venous occlusions compared to traditional methods.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Nephrology
Background:
- Central venous occlusive disease (CVOD) is a common complication in end-stage renal disease (ESRD) patients, often leading to dialysis access issues.
- Existing treatments for CVOD can be challenging, necessitating advanced endovascular techniques.
- The TriForce® Peripheral Crossing Set is a novel, reinforced, telescoping catheter designed to aid in crossing difficult central venous occlusions.
Purpose of the Study:
- To evaluate the efficacy of the TriForce® Peripheral Crossing Set for endovascular recanalization of central venous occlusions.
- To compare the technical success rates and outcomes of using the TriForce set versus traditional wire/catheter sets.
Main Methods:
- A single-center retrospective study involving 37 patients and 56 recanalization attempts over 17 months.
- Patients were divided into two groups: those treated with traditional wire/catheter sets (40 attempts) and those treated with the TriForce catheter set (16 attempts).
- Technical success rates, procedural data, and patient outcomes were compared between the two groups.
Main Results:
- The TriForce catheter set demonstrated a significantly higher technical success rate (69%) compared to traditional sets (38%) (P=0.04).
- Four patients were successfully recanalized with the TriForce set after prior failure with traditional methods.
- While fluoroscopy time and radiation dose were higher with the TriForce set, 1-year freedom from reintervention was comparable (60% vs. 44%).
Conclusions:
- The TriForce reinforced telescoping catheter set is an effective adjunct for improving recanalization rates in central venous occlusive disease.
- This novel device shows promise in managing complex venous occlusions, particularly in patients with ESRD.
- Further prospective studies may be warranted to confirm these findings and optimize its use.
Background:
Central venous occlusive disease (CVOD) is a prevalent problem in patients with end-stage renal disease (ESRD) and can lead to access malfunction or ligation for symptomatic relief. The purpose of this study is to evaluate the efficacy of the TriForce® Peripheral Crossing Set (Cook Medical), a novel reinforced telescoping catheter set designed to provide additional support for crossing difficult central venous occlusions.
Methods:
This is a single-center retrospective study from a quaternary referral center. We identified 37 patients over a 17-month period who underwent 56 attempts at endovascular recanalization for the treatment of central venous occlusion. Technical success rates, procedural data, and outcomes were compared between those undergoing recanalization using traditional wire/catheter sets versus the TriForce catheter set.
Results:
Average age was 48 ± 2 years. Comorbidities were similar between the two cohorts and included ESRD (61%), deep venous thrombosis (30%), and May-Thurner syndrome (7%). Forty attempts were made with traditional wire/catheter sets and 16 attempts with the TriForce catheter set to treat 2.1 ± 0.2 and 1.9 ± 0.3 occluded venous segments, respectively (P = 0.74). Technical success rates were significantly higher for the group undergoing recanalization using the TriForce catheter (69% versus 38%, P = 0.04) and 4 patients were successfully recanalized using the TriForce catheter set after a failed attempt with traditional wire/catheter sets. Mean fluoroscopy time and radiation dose were 13 ± 3 min and 14,623 ± 2,775 μGy∗m2 for traditional techniques versus 30 ± 6 min and 30,408 ± 10,433 μGy∗m2 for the novel telescoping catheter set (P = 0.01 and 0.09, respectively). Freedom from reintervention at 1 year was 60% for the TriForce cohort versus 44% for the traditional wire/catheter cohort (P = 0.25).
Conclusions:
The novel TriForce reinforced telescoping catheter set is a useful adjunct that may improve recanalization rates of CVOD compared with traditional wire/catheter sets.
Related Concept Videos
Venous Thrombosis III: Interprofessional Care
Cardiac Catheterization IV: Nursing Management
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

