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Inter-reviewer Variability in Interpretation of pH-Impedance Studies: The Wingate Consensus
C Prakash Gyawali1, Benjamin Rogers1, Marzio Frazzoni2
1Division of Gastroenterology, Washington University School of Medicine, St Louis, Missouri.
Abstract:
Ambulatory pH-impedance monitoring evaluates gastroesophageal reflux disease (GERD) symptoms that persist despite empiric treatment trials.1 Although automated analysis of pH-impedance monitoring is known to overestimate non-acid reflux episodes,2 even experts may disagree on individual reflux episodes,3,4 and accurate identification of postreflux swallow-induced peristaltic wave (PSPW). We hypothesized that a formal consensus meeting between expert pH-impedance reviewers would establish definitive criteria for identification of reflux episodes and PSPW, and improve inter-reviewer variability.
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