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Related Concept Videos

Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

961
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
961
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

551
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
551
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

542
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
542
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

202
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
202
Cells and Secretions of the Pancreas01:16

Cells and Secretions of the Pancreas

4.0K
The pancreas, a vital organ within the abdominal cavity, plays dual roles in the digestive and endocrine systems, collaborating with exocrine and endocrine cells to maintain optimal digestion and blood sugar levels.
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
Concurrently, the dispersed clusters of endocrine cells throughout the...
4.0K
Pancreas01:19

Pancreas

1.8K
The pancreas, an essential organ in the human body, is a pinkish-gray elongated structure located posterior to the stomach. It extends laterally from the duodenum towards the spleen and is firmly bound to the posterior wall of the abdominal cavity. The organ's surface has a lumpy, lobular texture that gives it a unique appearance.
The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short...
1.8K

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Related Experiment Video

Updated: Dec 9, 2025

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
06:35

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

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Acute pancreatitis.

Lotte Boxhoorn1, Rogier P Voermans1, Stefan A Bouwense2

  • 1Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

Lancet (London, England)
|September 6, 2020
PubMed
Summary
This summary is machine-generated.

Acute pancreatitis is a severe disease where outcomes depend on organ failure and infection. Recent advances favor multidisciplinary, minimally invasive treatments for this condition.

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Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
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Area of Science:

  • Gastroenterology and Hepatology
  • Critical Care Medicine

Background:

  • Acute pancreatitis presents unpredictable and potentially lethal clinical courses.
  • Prognosis is significantly influenced by the development of organ failure and secondary infections in pancreatic necrosis.
  • Despite advancements in critical care, severe acute pancreatitis continues to exhibit high mortality rates.

Purpose of the Study:

  • To review the latest evidence on diagnostic strategies for acute pancreatitis.
  • To outline current therapeutic approaches for acute pancreatitis.
  • To provide an updated overview of managing severe acute pancreatitis.

Main Methods:

  • Literature review of recent studies on acute pancreatitis diagnosis and treatment.
  • Analysis of current multidisciplinary and minimally invasive treatment modalities.
  • Synthesis of evidence on critical care and management of complications.

Main Results:

  • Diagnostic strategies have evolved, aiding in early risk stratification.
  • Minimally invasive techniques and tailored treatments are increasingly adopted.
  • Despite improved care, challenges in managing severe cases and preventing mortality persist.

Conclusions:

  • Effective management of acute pancreatitis requires a multidisciplinary and tailored approach.
  • Early diagnosis and timely intervention are crucial for improving patient outcomes.
  • Continued research is needed to further reduce mortality in severe acute pancreatitis.