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Subcutaneous granuloma annulare induced by acetazolamide
Maria Jose Guimaraes1, Joana Gomes1, Regina Caldas1
1Department of Dermatology and Venereology, Hospital de Braga, Braga, Portugal.
Abstract:
A 9-year-old boy presented with recurring subcutaneous nodules on both legs and knees temporally related each time to acetazolamide treatment for idiopathic intracranial hypertension. A biopsy of one of the lesions revealed palisaded granulomas in the hypodermis around necrobiotic collagen and interstitial accumulation of mucin, compatible with subcutaneous granuloma annulare (SGA). To the best of our knowledge, this is the first case that establishes an association between SGA and acetazolamide.
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