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Psychiatric Medications and Hypertension
1Department of Psychiatry and Behavioral Neuroscience, Wayne State University School of Medicine, Detroit, MI, USA. mmorreale@med.wayne.edu.
Current Hypertension Reports
|September 7, 2020
Summary
Psychiatric medications can affect blood pressure through direct side effects or metabolic impacts. Careful monitoring and management are crucial for patients with hypertension and psychiatric disorders to reduce cardiovascular risks.
Area of Science:
- Pharmacology
- Cardiology
- Psychiatry
Background:
- Patients with severe psychiatric illness face higher mortality and earlier death from cardiovascular disease.
- Inadequate medical care for hypertension is common in this population.
- Psychiatric medications can influence blood pressure directly or indirectly.
Purpose of the Study:
- To review psychiatric medications impacting blood pressure in adults.
- To discuss metabolic impacts and drug interactions affecting blood pressure.
- To examine interactions between psychiatric drugs and antihypertensive agents.
Main Methods:
- Literature review of psychiatric medications and their effects on blood pressure.
- Analysis of metabolic impacts and drug interactions.
- Examination of interactions with antihypertensive therapies.
Main Results:
- Esketamine may transiently increase blood pressure but typically doesn't require antihypertensive treatment.
- Antipsychotic medications can cause negative metabolic impacts within the first month, necessitating early monitoring.
- No absolute contraindications exist for using psychiatric medications in hypertensive patients.
Conclusions:
- Physicians must be aware of the increased cardiovascular risk in psychiatric patients with hypertension.
- Thorough assessment and management of blood pressure are vital.
- Proactive monitoring and treatment can mitigate risks associated with psychiatric medications and hypertension.
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