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Related Experiment Videos

Human intervertebral disc: structure and function.

M D Humzah1, R W Soames

  • 1Department of Anatomy and Human Biology, King's College London, Strand, England.

The Anatomical Record
|April 1, 1988
PubMed
Summary
This summary is machine-generated.

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The intervertebral disc is a dynamic, heterogeneous structure crucial for spinal column function. It possesses self-maintenance and regenerative capabilities, highlighting its active role in spinal health.

Area of Science:

  • Anatomy and Physiology
  • Biomechanical Engineering

Background:

  • The intervertebral disc (IVD) is a complex spinal structure.
  • Understanding its development, vascularization, and innervation is key to its function.

Purpose of the Study:

  • To provide a detailed review of the intervertebral disc's structure and function.
  • To explore the relationship between the disc's components and its biomechanical properties.
  • To highlight the dynamic and regenerative nature of the IVD.

Main Methods:

  • Review of existing literature on intervertebral disc anatomy, physiology, and biomechanics.
  • Detailed examination of the nucleus pulposus, annulus fibrosus, and cartilage end plates.
  • Analysis of the relationship between structural, biochemical, and functional aspects.

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Main Results:

  • The IVD comprises distinct regions (nucleus pulposus, annulus fibrosus, end plates) with a continuous transition.
  • Structural and biochemical elements are intrinsically linked to the disc's function and dynamic response to loads.
  • The IVD is an active, heterogeneous structure interacting with vertebral bodies, influencing spinal kinematics.

Conclusions:

  • The intervertebral disc is not static but a dynamic, responsive unit integral to the vertebral column.
  • The disc exhibits self-maintenance, repair, and regenerative properties, crucial for spinal health and function.