Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Brain Markers of Resilience to Psychosis in High-Risk Individuals: A Systematic Review and Label-Based Meta-Analysis of Multimodal MRI Studies.

Brain sciences·2025
Same author

Probabilistic and rich individual working memories revealed by a betting game.

Scientific reports·2023
Same author

Cell Proliferation and Cell Death Levels in the Dentate Gyrus Correlate with Home Range Size Among Adult Male Meadow Voles.

Neuroscience·2023
Same author

Auditory hallucinations, childhood sexual abuse, and limbic gray matter volume in a transdiagnostic sample of people with psychosis.

Schizophrenia (Heidelberg, Germany)·2022
Same author

Cellular and Extracellular White Matter Abnormalities in Obsessive-Compulsive Disorder: A Diffusion Magnetic Resonance Imaging Study.

Biological psychiatry. Cognitive neuroscience and neuroimaging·2021
Same author

Spontaneous Infraslow Fluctuations Modulate Hippocampal EPSP-PS Coupling.

eNeuro·2018

Related Experiment Video

Updated: Dec 9, 2025

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents
09:01

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents

Published on: July 8, 2015

13.0K

Interindividual differences in memory system local field potential activity predict behavioral strategy on a

Joshua E Goldenberg1, Stergiani Lentzou1, Lyn Ackert-Smith1

  • 1Program in Neuroscience, Middlebury College, Middlebury, Vermont, USA.

Hippocampus
|September 7, 2020
PubMed
Summary

Navigation strategies in rats depend on distinct brain activity patterns. The hippocampus and striatum show unique coordination, influencing whether rats use place or response strategies, highlighting how brain systems bias behavior.

Keywords:
LFPmultiple memory systemsnavigationneuronal oscillationsrat

More Related Videos

Simultaneous Monitoring of Wireless Electrophysiology and Memory Behavioral Test as a Tool to Study Hippocampal Neurogenesis
07:25

Simultaneous Monitoring of Wireless Electrophysiology and Memory Behavioral Test as a Tool to Study Hippocampal Neurogenesis

Published on: August 20, 2020

4.0K
T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice
17:45

T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice

Published on: February 26, 2012

40.6K

Related Experiment Videos

Last Updated: Dec 9, 2025

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents
09:01

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents

Published on: July 8, 2015

13.0K
Simultaneous Monitoring of Wireless Electrophysiology and Memory Behavioral Test as a Tool to Study Hippocampal Neurogenesis
07:25

Simultaneous Monitoring of Wireless Electrophysiology and Memory Behavioral Test as a Tool to Study Hippocampal Neurogenesis

Published on: August 20, 2020

4.0K
T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice
17:45

T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice

Published on: February 26, 2012

40.6K

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Behavioral Biology

Background:

  • Navigating environments involves diverse strategies, including hippocampal place strategies (cognitive maps) and striatal response strategies (body turns).
  • Multiple memory systems aid navigation, but their interaction in generating unified behavior is not fully understood.

Purpose of the Study:

  • To investigate the neural mechanisms underlying the interaction between hippocampal and striatal systems in strategy selection during navigation.
  • To identify distinct patterns of brain activity associated with place versus response strategies in rats.

Main Methods:

  • Trained 20 male Sprague-Dawley rats on a dual-solution T-maze.
  • Simultaneously recorded local field potentials (LFPs) from the dorsolateral striatum and dorsal hippocampus.
  • Analyzed LFP activity patterns and used support vector machines to predict behavioral strategies.

Main Results:

  • Eight rats used a place strategy, while 12 used a response strategy.
  • Place and response strategists showed distinct patterns of striatal-hippocampal LFP activity, including theta phase relationships and cross-frequency coherence.
  • These neural activity patterns were present during habituation and learning and could predict behavioral strategy.

Conclusions:

  • Distinct patterns of neural activity across the hippocampus and striatum bias behavioral strategy selection.
  • Interindividual differences in navigation behavior are linked to specific striatal-hippocampal activity regimes.
  • This research clarifies how multiple memory systems interact to influence behavioral output.