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Quantitative Sensory Testing Protocols to Evaluate Central and Peripheral Sensitization in Knee OA: A Protocol for a
Benjamin Rudy-Froese1, Jonathan Rankin1, Curtis Hoyt1
1McMaster University, School of Rehabilitation Sciences, Hamilton, Canada.
Current Rheumatology Reviews
|September 8, 2020
Summary
Quantitative sensory testing (QST) for knee osteoarthritis (OA) lacks standardized protocols. This review identifies common QST methods and sensitization definitions, highlighting the need for evidence-based guidelines.
Area of Science:
- Neuroscience
- Rheumatology
- Pain Management
Background:
- Quantitative sensory testing (QST) is crucial for assessing nervous system sensitization in knee osteoarthritis (OA).
- Current QST protocols lack standardization, leading to interpretation variability.
- Standardized methods are needed for reliable assessment of nociceptive signaling in knee OA.
Purpose of the Study:
- To identify diverse QST methodologies used in knee OA research.
- To understand how sensitization is defined in the context of knee OA.
- To synthesize common QST protocol elements and sensitization definitions.
Main Methods:
- Scoping review guided by established methodologies.
- Systematic search of Medical Literature Analysis and Retrieval System Online, EMBASE, CINAHL, and AMED databases.
- Independent data extraction focusing on QST protocols and sensitization definitions.
Main Results:
- Identification of various QST techniques employed in knee OA studies.
- Analysis of differing definitions of sensitization within the literature.
- Summary of commonalities and variations in current QST practices.
Conclusions:
- This review offers insights into prevalent QST methods for knee OA.
- It highlights the need for developing standardized, evidence-based QST protocols.
- Findings may guide future systematic reviews and primary research in the field.