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Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
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COVID-19 and Multiple Sclerosis: Predisposition and Precautions in Treatment
Shaghayegh Sadeghmousavi1,2, Nima Rezaei3,4,5
1Neuroimaging Network (NIN), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Abstract:
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading to Coronavirus disease 2019 (COVID-19), is not always confined to the respiratory tract, while patients with can develop neurological manifestations. The patients with multiple sclerosis (MS) pose challenges in this pandemic situation, because of the immunosuppressive medications they get and the fact that viral infections may contribute to MS exacerbation and relapses as an environmental factor in genetically predisposed individuals. Herein, possible consequences of COVID-19 which may carry for the MS patients and the underlying mechanisms of its impact are discussed.
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