Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multistep reactions with immobilized microorganisms.

B Bisping1, H J Rehm

  • 1Institut für Mikrobiologie, Westfälische Wilhelms-Universität Münster, Federal Republic of Germany.

Biotechnology and Applied Biochemistry
|April 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biologic processing of fossil fuels. Rśumé of the Bioconversion Session of ICCS'97.

Applied microbiology and biotechnology·1999
Same author

Changes in the contents of fat-soluble vitamins and provitamins during tempe fermentation.

International journal of food microbiology·1999
Same author

Biodegradation of 2-chloroethanol by freely suspended and adsorbed immobilized Pseudomonas putida US2 in soil.

Applied microbiology and biotechnology·1995
Same author

Development of a continuous system for the degradation of a cyanuric acid by absorbed Pseudomonas sp. NRRL B-12228.

Applied microbiology and biotechnology·1995
Same author

Utilization of chlorinated s-triazines by a new strain of Klebsiella pneumoniae.

Applied microbiology and biotechnology·1995
Same author

Vitamin B12 production by Citrobacter freundii or Klebsiella pneumoniae during tempeh fermentation and proof of enterotoxin absence by PCR.

Applied and environmental microbiology·1994
Same journal

Development and Validation of an ELISA Method for Quantification of HuB01 in Fermentation Products.

Biotechnology and applied biochemistry·2026
Same journal

Optimization and Characterization of Poly-γ-Glutamic Acid Production From a Locally Isolated Bacillus cereus ARM24.

Biotechnology and applied biochemistry·2026
Same journal

Isolation and Characterization of a Novel Microbacterium takaoensis Lipase for Nutritional and Textural Improvement of Pizza Dough.

Biotechnology and applied biochemistry·2026
Same journal

Targeting Amastigote and Trypomastigote Phases: Multi-Epitope Vaccine Strategy Against Trypanosoma cruzi.

Biotechnology and applied biochemistry·2026
Same journal

Novel Inhibitors Targeting Class B1 Metallo-β-Lactamases in Carbapenem-Resistant Acinetobacter baumannii.

Biotechnology and applied biochemistry·2026
Same journal

Formulation of PLA/Chitosan Copolymeric Nanocarriers Enhanced the Sustained and Targeted Drug Delivery of Cinnamic Acid: In Vitro Drug Optimization and In Vivo Biodistribution in Rat Model.

Biotechnology and applied biochemistry·2026
See all related articles

Immobilized microorganisms enable efficient semicontinuous and continuous processes for producing valuable compounds like glycerol and citric acid, and for degrading harmful xenobiotics in various wastewater types.

Area of Science:

  • Biotechnology
  • Biochemical Engineering
  • Environmental Microbiology

Background:

  • Immobilized microorganisms offer enhanced stability and reusability in bioprocesses.
  • Developing efficient continuous processes is crucial for industrial biotechnology and environmental remediation.
  • Previous methods faced limitations in scalability and efficiency for metabolite production and pollutant degradation.

Purpose of the Study:

  • To review new semicontinuous and continuous bioprocesses utilizing immobilized microorganisms.
  • To showcase applications in both product formation (primary and secondary metabolites) and xenobiotic degradation.
  • To evaluate the efficacy of these processes in diverse environments, including wastewater.

Main Methods:

  • Immobilization of microorganisms (Saccharomyces cerevisiae, Aspergillus niger, Claviceps purpurea) via adsorption and entrapment.

Related Experiment Videos

  • Development of semicontinuous and continuous reactor configurations.
  • Application of processes for glycerol, citric acid, ergot alkaloid production, and phenolic/4-chlorophenol degradation.

    • Main Results:

    • Successful semicontinuous glycerol production using Saccharomyces cerevisiae adsorbed on sintered glass.
    • Continuous citric acid production achieved with Aspergillus niger entrapped in calcium alginate.
    • Demonstrated production of secondary metabolites (ergot alkaloids) using immobilized Claviceps purpurea.
    • Effective continuous degradation of phenolic substances and 4-chlorophenol by immobilized microorganisms in artificial solutions and wastewater (sterile and nonsterile).

    Conclusions:

    • Immobilized microorganisms are highly effective for both continuous production of metabolites and degradation of xenobiotics.
    • These advanced bioprocesses show significant potential for industrial applications and environmental cleanup, even in complex wastewater matrices.
    • The reviewed technologies represent a significant advancement in applied microbiology and bioprocess engineering.