Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

1.0K
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
1.0K
Seizures: Classification01:13

Seizures: Classification

1.1K
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quality-of-life after risk-reducing mastectomy in women with increased risk of breast cancer: A longitudinal study.

Journal of genetic counseling·2026
Same author

Exploring the limits of 3D dopant localization in phosphor nanoparticles: A simulation-to-experiment perspective via through-focus HAADF-STEM.

Micron (Oxford, England : 1993)·2026
Same author

Multiscale Analysis of Mesial Temporal Lobe Epilepsy: Anatomo-Electrophysio-Pathologic Differentiation - CORRIGENDUM.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2025
Same author

Prenatal evaluation, diagnosis and management of fetal corpus callosal abnormalities: international Delphi consensus.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2025
Same author

Malnutrition Risk Is Associated With All-Cause Mortality and Chemotherapy Complications Among Adults Diagnosed With Diverse Cancer Types: A Retrospective Cohort Study.

Journal of the Academy of Nutrition and Dietetics·2025
Same author

Drivers' overall comfort experiences of reclined positions in a passenger car with an automated driving function.

Applied ergonomics·2025
Same journal

<sup>18</sup>F-FDG PET/MRI Multiparametric Imaging Features for Predicting MYCN Amplification Status in Children With High-Risk Neuroblastoma.

Revista de neurologia·2026
Same journal

Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Positive Juvenile Dermatomyositis Presenting With Predominant Joint Contractures.

Revista de neurologia·2026
Same journal

Association Between Immunotherapy and Generalization in Ocular Myasthenia Gravis as a Function of Antibody Status.

Revista de neurologia·2026
Same journal

Systematic Review and Meta-Analysis of the Efficacy of Fecal Microbiota Transplantation in Parkinson's Disease: An Exploration Based on UPDRS and Cognitive Scores.

Revista de neurologia·2026
Same journal

EEG Quantification: A New Dawn for an Old Tool.

Revista de neurologia·2026
Same journal

The Dual Role of VEGF in Intracerebral Haemorrhage: From Pathological Mechanisms to Therapeutic Opportunities.

Revista de neurologia·2026
See all related articles

Related Experiment Video

Updated: Dec 9, 2025

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
11:29

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

1.7K

[Temporal plus epilepsy: a review].

J Toro-Pérez1, A Suller-Martí1, M Herrera1

  • 1Western University, London, Ontario, Canadá.

Revista De Neurologia
|September 8, 2020
PubMed
Summary
This summary is machine-generated.

Temporal plus epilepsy involves seizures originating beyond the temporal lobe, impacting surrounding brain areas. Understanding these complex neural networks is crucial for diagnosis and treatment, as it

More Related Videos

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

12.7K
Using a Bipolar Electrode to Create a Temporal Lobe Epilepsy Mouse Model by Electrical Kindling of the Amygdala
09:49

Using a Bipolar Electrode to Create a Temporal Lobe Epilepsy Mouse Model by Electrical Kindling of the Amygdala

Published on: June 29, 2022

3.0K

Related Experiment Videos

Last Updated: Dec 9, 2025

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
11:29

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

1.7K
Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

12.7K
Using a Bipolar Electrode to Create a Temporal Lobe Epilepsy Mouse Model by Electrical Kindling of the Amygdala
09:49

Using a Bipolar Electrode to Create a Temporal Lobe Epilepsy Mouse Model by Electrical Kindling of the Amygdala

Published on: June 29, 2022

3.0K

Area of Science:

  • Neurology
  • Epileptology
  • Neurosurgery

Background:

  • Temporal plus epilepsy is focal epilepsy where the epileptogenic zone extends beyond the temporal lobe, affecting adjacent regions like the insula and orbitofrontal cortex.
  • Risk factors include prior brain trauma, tonic-clonic seizures, and central nervous system infections, potentially leading to complex neural network formation.
  • Clinical presentation varies based on the epileptogenic zone's location and propagation to mesial temporal structures.

Purpose of the Study:

  • To provide an updated review of temporal plus epilepsy.
  • To highlight diagnostic challenges and current methodologies.
  • To discuss its significance in the context of temporal lobe epilepsy surgery outcomes.

Main Methods:

  • Review of existing literature on temporal plus epilepsy.
  • Analysis of clinical manifestations and neuroimaging findings.
  • Evaluation of diagnostic tools including video-electroencephalography (VEEG), magnetoelectroencephalography (MEEG), MRI, and stereoelectroencephalography (SEEG).

Main Results:

  • Temporal plus epilepsy involves complex hippocampal and extrahypocampic neural networks.
  • VEEG typically shows temporal lobe involvement with rapid spread to adjacent areas.
  • MEEG may serve as an early diagnostic biomarker due to reduced muscle artifact.
  • Brain MRI is often non-specific; SEEG is the preferred invasive diagnostic method.
  • Temporal plus epilepsy is a significant factor in up to 30% of temporal lobe epilepsy surgery failures.

Conclusions:

  • Temporal plus epilepsy presents unique diagnostic and therapeutic challenges due to its extended epileptogenic zone.
  • Accurate localization using methods like SEEG is critical for surgical planning.
  • Recognizing temporal plus epilepsy is essential for improving surgical success rates in refractory epilepsy cases.