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A new era of rational malaria vaccine development
Jessica A Engel1, Christian R Engwerda1
1Immunology and Infection Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Immunology and Cell Biology
|September 8, 2020
Abstract:
Holz et al. report a glycolipid-conjugate vaccine that provides sterile immunity in mice against Plasmodium berghei ANKA sporozoite challenge by inducing long-lasting tissue-resident memory (TRM) CD8+ T cells in the liver.
