Related Experiment Videos
Recognition and management of disseminated intravascular coagulation in horses
1Department of Large Animal Medicine, University of Georgia College of Veterinary Medicine, Athens.
The Veterinary Clinics of North America. Equine Practice
|April 1, 1988
Insights
This review explains normal hemostasis and disseminated intravascular coagulation (DIC) in horses. It covers DIC pathogenesis, clinical and laboratory signs, diagnosis, and treatment for equine veterinary professionals.
Area of Science:
- Veterinary Medicine
- Equine Health
- Hematology
Background:
- Hemostasis is a complex process crucial for maintaining vascular integrity.
- Disseminated intravascular coagulation (DIC) is a life-threatening condition with significant implications in equine practice.
Purpose of the Study:
- To provide a comprehensive understanding of normal hemostasis in horses.
- To elucidate the pathogenesis, clinical, and laboratory manifestations of DIC in horses.
- To outline current diagnostic and therapeutic strategies for equine DIC.
Main Methods:
- Literature review of normal hemostasis.
- Review of pathogenesis and clinical presentations of equine DIC.
- Summary of diagnostic criteria and treatment protocols for equine DIC.
Main Results:
- Normal hemostasis involves intricate interactions of platelets, coagulation factors, and fibrinolysis.
- Equine DIC is characterized by widespread activation of coagulation, leading to thrombosis and hemorrhage.
- Early recognition and prompt intervention are critical for improving outcomes in horses with DIC.
Conclusions:
- A thorough understanding of hemostasis is fundamental for diagnosing and managing DIC in horses.
- DIC presents with diverse clinical signs, necessitating careful laboratory evaluation for accurate diagnosis.
- Effective management of equine DIC requires addressing the underlying cause and supportive care.
Abstract:
This article reviews normal hemostasis in order to provide the reader with the basis for understanding the pathogenesis and manifestations (both clinical and laboratory) of disseminated intravascular coagulation (DIC) in horses. DIC is subsequently discussed. The diagnosis and treatment of DIC in horses are also described.