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Updated: Dec 9, 2025

Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
[D-mannose for prevention and treatment of lower urinary tract infection: pathogenetic basics and clinical results]
I V Kuz'min1,2, M N Slesarevskaya1,2, S H Al-Shukri1,2
1Department of Urology of First Pavlov Saint-Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation, Saint Petersburg, Russia.
Abstract:
Non-antibacterial methods of prevention and treatment of lower urinary tract infection are described in the article. The current view on the mechanism of treatment effect of D-mannose is presented, which contributes to the prevention of bacterial invasion. Pathogenetic concepts for using D-mannose as specific antiadhesin or a competitive blocker of bacterial invasion is provided. In addition, we discussed the results of basic and clinical studies, proving the efficiency of D-mannose for prevention and treatment of lower urinary tract infection.
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