Reduced Growth Hormone Response to Anaerobic Exercise Among Children With Overweight and Obesity
Duha Hejla1, Nitzan Dror, Michal Pantanowitz
1Child Health and Sports Center, Pediatric Department, Meir Medical Center, Sackler School of Medicine, Tel-Aviv University, Israel.
Insights
Children with overweight and obesity show a reduced growth hormone (GH) response to anaerobic exercise compared to normal-weight children. This suggests that anaerobic interval training may not be optimal for stimulating GH in obese youth.
Area of Science:
- Pediatric Endocrinology
- Exercise Physiology
- Obesity Research
Background:
- Growth hormone (GH) is crucial for childhood development.
- Overweight and obesity can impact endocrine function.
- The effect of anaerobic exercise on GH secretion in pediatric populations with overweight/obesity is not well understood.
Purpose of the Study:
- To compare the GH secretion response to a modified Wingate anaerobic test (WAnT) in children with overweight/obesity versus normal-weight children.
- To determine if anaerobic exercise adequately stimulates GH release in overweight and obese children.
Main Methods:
- A modified repeated Wingate anaerobic test (WAnT) was administered to 15 children with overweight/obesity and 10 normal-weight children.
- Blood samples were collected pre-exercise and at 15, 30, 45, and 60 minutes post-exercise to measure GH and lactate levels.
Main Results:
- Both groups showed a significant increase in GH levels post-exercise.
- The increase in GH levels was significantly greater in normal-weight children compared to those with overweight/obesity (p < 0.003).
- Fewer overweight/obese children (2/15) reached the GH sufficiency threshold compared to normal-weight children (7/10).
Conclusions:
- Children with overweight and obesity exhibit a blunted GH response to anaerobic exercise.
- Anaerobic interval-type training may be insufficient to stimulate adequate GH levels in this population.
- Further research is needed to identify optimal exercise strategies for GH stimulation in pediatric obesity.
Abstract:
Hejla, D, Dror, N, Pantanowitz, M, Nemet, D, and Eliakim, A. Reduced growth hormone response to anaerobic exercise among children with overweight and obesity. J Strength Cond Res 36(8): 2194-2197, 2022-The aim of the present study was to examine the effect of an anaerobic exercise test on growth hormone (GH) secretion in children with overweight and obesity compared with children with normal weight. Fifteen children with overweight (body mass index percentile [BMI%ile] ≥85 < 95) and obesity (BMI%ile ≥95) and 10 children with normal weight (BMI%ile >5 < 85) participated in the study. Subjects performed a modification of the Wingate anaerobic test (WAnT), with 10 bouts of 15-second cycling separated by 1 minute of rest. Blood samples for GH and lactate were collected before and 15, 30, 45, and 60 minutes after the beginning of the exercise test. There was a significant increase in GH levels following the modified repeated WAnT in both groups, but the increase in GH levels was significantly greater among the normal weight children compared with those with overweight and obesity ( p < 0.003). Seven of the 10 subjects with normal weight had GH increase above the threshold for GH sufficiency compared with only 2 subjects with overweight and obesity. Growth hormone response to the modified repeated WAnT was significantly reduced among children with overweight and obesity compared with those with normal weight. Anaerobic interval-type training may not be a sufficient exercise alternative to stimulate appropriate GH levels among children with obesity.
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