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Related Concept Videos

Pigmentation01:19

Pigmentation

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
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Updated: Dec 9, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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Camouflaging vitiligo using a spray tan.

Alexa B Steuer, John G Zampella1

  • 1The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, NY. John.Zampella@nyulangone.org.

Dermatology Online Journal
|September 8, 2020
PubMed
Summary
This summary is machine-generated.

Spray tans offer a safe and effective temporary cosmetic solution for vitiligo patients. This method can temporarily improve skin pigmentation and reduce patient distress associated with depigmentation.

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Area of Science:

  • Dermatology
  • Cosmetic Science

Background:

  • Vitiligo is a depigmenting skin disorder causing significant patient distress.
  • Effective cosmetic treatment options for vitiligo are challenging to find.

Observation:

  • A 60-year-old patient with vitiligo was treated using a spray tan.
  • The patient experienced temporary improvement in skin pigmentation.

Findings:

  • Spray tanning provides a reasonable, safe, and effective camouflage for vitiligo.
  • This cosmetic approach addresses patient concerns regarding depigmentation.

Implications:

  • Spray tanning can be a valuable tool in the management of vitiligo.
  • It offers a non-invasive, temporary solution to improve cosmetic appearance and patient well-being.