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Lesions of testis and epididymis associated with prenatal diethylstilbestrol exposure
B C Bullock1, R R Newbold, J A McLachlan
1National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709.
Environmental Health Perspectives
|April 1, 1988
Abstract:
Cryptorchidism and retention of Müllerian duct structures occur with high frequency among the male offspring of CD-1 mice treated with 100 micrograms diethylstilbestrol/kg body weight on days 9 through 16 of pregnancy. Hyperplasia of the rete testis and Müllerian duct structures were found in many of the DES-treated male mice, as was a low but significant number of reproductive tract neoplasms.