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Testing for SARS-CoV-2 (COVID-19): A General Review
Eric W Tang1, April M Bobenchik1, Shaolei Lu1
1Department of Pathology and Laboratory Medicine, Alpert Medical School of Brown University, Providence, RI.
Abstract:
The rampant COVID-19 pandemic has strained the testing capabilities of healthcare centers across the country. Several nucleic acid and serologic assays are available or currently being developed to meet the growing demand for large-scale testing. This review summarizes the developments of commonly used testing methods and their strategic use in clinical diagnosis and epidemiologic surveillance. This review will cover the basic virology of SARS-CoV-2, nucleic acid amplification testing, serology, antigen testing, as well as newer testing methods such as CRISPR-based assays.
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