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Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Related Experiment Video

Updated: Dec 9, 2025

Y-27632 Enriches the Yield of Human Melanocytes from Adult Skin Tissues
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Yellow skin without jaundice.

Anders Batman Mjelle, Hallvard Martin Reigstad

    Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
    |September 9, 2020
    PubMed
    Summary
    This summary is machine-generated.

    Prompt assessment of infant jaundice is crucial. Yellow skin or sclerae in infants beyond two weeks necessitates immediate medical evaluation to rule out serious conditions like biliary atresia, even without discolored stools.

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    Area of Science:

    • Neonatal Medicine
    • Pediatric Gastroenterology

    Background:

    • Infant jaundice, characterized by yellowing of the skin and sclerae, requires careful evaluation.
    • Conjugated hyperbilirubinemia is a critical indicator that necessitates ruling out serious underlying conditions.

    Purpose of the Study:

    • To emphasize the importance of examining both sclerae and skin in jaundiced infants.
    • To highlight the diagnostic significance of persistent jaundice beyond two weeks of age.

    Main Methods:

    • Clinical examination of infants presenting with yellow coloration.
    • Assessment of jaundice duration and presence of associated symptoms like discolored stools.

    Main Results:

    • Yellow sclerae may precede yellow skin in infants with conditions like biliary atresia.
    • Discolored stools, while classic, are not consistently present in biliary atresia.

    Conclusions:

    • Infants over two weeks old with yellow skin require immediate assessment for conjugated hyperbilirubinemia.
    • Prompt medical evaluation is essential for infants with persistent jaundice, irrespective of stool color, to diagnose conditions such as biliary atresia.