Related Experiment Video
Updated: Dec 9, 2025

Preparation of Agar Bead Embedded Mycobacterium abscessus to Inoculate Immunocompetent Mice Intratracheally
Published on: April 25, 2025
Rare case of Prevotella pleuritidis lung abscess
Abuzar Ali Asif1, Moni Roy2,3, Sharjeel Ahmad4
1Internal Medicine, University of Illinois College of Medicine at Peoria, Peoria, Illinois, USA.
Abstract:
Prevotella genus comprises of obligate anaerobic, gram-negative bacteria that are commensal organisms of oral cavity, gut and vaginal mucosa. Although many Prevotella species have well-established pathogenicity with respect to pulmonary infections, rarely has Prevotella pleuritidis been isolated as a cause of lung abscess. We present a rare case of left lower lobe lung abscess due to P. pleuritidis identified using next-generation sequencing of microbial cell-free DNA testing. A brief review of the literature regarding Prevotella species pulmonary infections, use of next-generation cell-free DNA testing early in the evaluation, antibiotic susceptibility and resistance is also a part of this report.
Insights
This study reports a rare case of lung abscess caused by Prevotella pleuritidis. Next-generation sequencing identified the bacteria, highlighting its potential role in pulmonary infections.
Area of Science:
- Microbiology
- Infectious Diseases
- Genomics
Background:
- The Prevotella genus includes anaerobic, Gram-negative bacteria commonly found in human mucosal environments.
- While some Prevotella species are known pathogens, Prevotella pleuritidis is rarely implicated in lung infections.
Observation:
- A rare case of left lower lobe lung abscess is presented.
- Prevotella pleuritidis was identified as the causative agent.
Findings:
- Next-generation sequencing of microbial cell-free DNA was utilized for early and accurate diagnosis.
- The report includes a review of Prevotella species in pulmonary infections, diagnostic methods, and antibiotic resistance patterns.
Implications:
- This case underscores the importance of considering less common Prevotella species in lung abscess etiology.
- Advanced sequencing techniques can aid in the rapid identification of pathogens, guiding treatment decisions for pulmonary infections.
Related Concept Videos
Pneumonia III: Complications and Assessment
Pneumothorax-II
Clinical Manifestations:
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pleura of the Lungs
Pneumothorax-I
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

