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Lymphokines and interleukins.

A S Hamblin1

  • 1Department of Immunology, United Medical and Dental Schools, London, U.K.

Immunology. Supplement
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

Recombinant DNA technology enables the study of lymphokines, revealing their diverse and synergistic effects on various cells and organs. This research highlights the biological significance of these immune signaling molecules.

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Area of Science:

  • Immunology
  • Molecular Biology
  • Biochemistry

Background:

  • Lymphokines are crucial immune signaling molecules.
  • Investigating lymphokines has been challenging due to their heterogeneity.
  • Recombinant DNA technology offers a solution for obtaining pure lymphokines.

Purpose of the Study:

  • To review the biochemical and biological properties of lymphokines.
  • To discuss the diverse effects of lymphokines on target cells and organs.
  • To explore the biological significance of lymphokine actions.

Main Methods:

  • Application of recombinant DNA technology for lymphokine production.
  • Review of existing literature on lymphokine properties.
  • Analysis of experimental data on lymphokine effects.

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Main Results:

  • Homogeneous lymphokine preparations are now available for research.
  • Lymphokines exhibit diverse effects on multiple cell types.
  • Synergistic interactions between lymphokines have been observed.

Conclusions:

  • Recombinant lymphokines facilitate detailed experimental investigation.
  • Lymphokines play a significant role in regulating immune responses.
  • Understanding lymphokine functions is key to advancing immunology.