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Mechanistic Multilayer Quantitative Model for Nonlinear Pharmacokinetics, Target Occupancy and Pharmacodynamics

Tomoki Yoneyama1, Sho Sato2, Andy Sykes3

  • 1Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan. tomoki.yoneyama@takeda.com.

Pharmaceutical Research
|September 9, 2020
PubMed
Abstract

Keywords:
D-amino acid oxidase inhibitorPK/PD, multilayer quantitative modelTAK-831target occupancy

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