Influence of Cap Thickness on Opaque Bubble Layer Formation in SMILE: 110 Versus 140 µm

To investigate the impact of cap thickness on the formation of an opaque bubble layer (OBL) during small incision lenticule extraction procedures.

In total, 100 eyes from 50 patients were prospectively examined. One of two corneal cap thicknesses was randomly assigned to each eye and differed in the contralateral eye: 110 µm in one eye and 140 µm in the other. OBL area and density were quantitatively assessed.

The proportion of OBL areas in the anterior lenticule plane was 11.70% ± 7.35% in the 110-µm group, which was significantly higher than the 140-µm group (6.64% ± 4.68%, P < .001). For OBL areas located in the posterior lenticule plane, mean areas for the 110-µm group were also higher than those for the 140-µm group (1.32% ± 1.20% and 0.94% ± 0.59%, respectively; P = .002). Mean gray values of the OBL in the posterior lenticule plane were slightly different between the two groups (P < .001), but no significant difference in OBL of the anterior lenticule plane was observed (P = .055). Eyes with a 110-µm cap thickness had more focal OBLs, revealed by cap scanning (chi-square = 10.256, P = .001).

Corneal cap thickness is predictive of opaque bubble layer during small incision lenticule extraction procedures. [J Refract Surg. 2020;36(9):592-596.].