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Speciation and the developmental alarm clock.

Asher D Cutter1, Joanna D Bundus2

  • 1Department of Ecology & Evolutionary Biology, University of Toronto, Toronto, Canada.

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|September 9, 2020
PubMed
Summary
This summary is machine-generated.

Speciation occurs when genomes diverge, leading to hybrid infertility. The timing of development influences hybrid dysfunction, offering insights into evolutionary developmental biology and speciation genetics.

Keywords:
developmental biologyevo-devogenetic networksgeneticsgenomicsmolecular evolutionreproductive isolationspeciation

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Area of Science:

  • Evolutionary Developmental Biology
  • Speciation Genetics
  • Molecular Evolution

Background:

  • New species form through genome divergence, a process influenced by genetic changes in development.
  • Hybrid dysfunction, leading to infertility or inviability, signals the emergence of new species with intrinsic post-zygotic reproductive isolation.
  • The ontogenetic timing of gene expression critically affects hybrid incompatibilities.

Purpose of the Study:

  • To explore the relationship between speciation and development, focusing on genetic networks, fitness landscapes, and developmental system drift.
  • To connect evolutionary developmental biology ('evo-devo') and speciation genetics.
  • To assess models predicting the ontogenetic timing of reproductive isolation.

Main Methods:

  • Theoretical modeling of speciation and development.
  • Analysis of genetic network features and fitness landscapes.
  • Investigating developmental system drift and gene expression timing.

Main Results:

  • Developmental timing significantly influences the manifestation of hybrid incompatibilities.
  • Predictive models for the ontogenetic timing of reproductive isolation can be developed.
  • A synthetic perspective links macroevolutionary patterns to microevolutionary processes and molecular mechanisms.

Conclusions:

  • Understanding the ontogeny of hybrid incompatibilities is key to linking evolutionary patterns and processes.
  • This research can reveal new rules governing speciation and the molecular evolution of development.
  • The interplay between development and genetics provides a framework for studying the emergence of new species.