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Redefining Pregnancy-Induced Rhinitis.

Tomislav Baudoin1,2, Tena Šimunjak1,3, Nikolina Bacan2

  • 1Department of Otorhinolaryngology & Head and Neck Surgery, University Hospital Center Sestre Milosrdnice, Zagreb, Croatia.

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|September 9, 2020
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Summary

Pregnancy-induced rhinitis (PIR) affects over 30% of pregnant women, causing nasal symptoms that impact quality of life. Symptoms typically resolve after delivery, but PIR can influence pre-existing sinonasal conditions.

Keywords:
analysiscomorbiditydifferential diagnosisetiologypregnancyprevalencequality of lifequestionnairerhinitissymptoms

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Area of Science:

  • Obstetrics and Gynecology
  • Otolaryngology
  • Allergy and Immunology

Background:

  • Pregnancy-induced rhinitis (PIR) is a distinct condition characterized by nasal symptoms arising during pregnancy and resolving postpartum.
  • It is a form of non-allergic rhinitis not present before gestation.

Purpose of the Study:

  • To determine the prevalence of PIR.
  • To characterize the symptoms, duration, and impact on quality of life associated with PIR.
  • To investigate the relationship between PIR and pre-existing sinonasal diseases.

Main Methods:

  • An ambidirectional longitudinal cohort study involving 681 pregnant women.
  • Questionnaires administered postpartum to assess nasal symptoms.
  • Interviews conducted 30 days later for women with symptoms to record duration and quality.

Main Results:

  • PIR prevalence was 31.86%.
  • Nasal obstruction was the most frequent symptom, followed by rhinorrhea and sneezing.
  • PIR negatively impacted the quality of life for 53.9% of affected women, with a median symptom duration of 4 months.
  • PIR was more common in women carrying female fetuses and could influence pre-existing sinonasal conditions.

Conclusions:

  • Pregnancy-induced rhinitis is a common condition with diverse symptoms significantly affecting maternal quality of life.
  • A new definition for PIR is proposed based on these findings.
  • PIR warrants recognition as a distinct clinical entity during pregnancy.